Las Vegas Raiders at Los Angeles Chargers, October 4, 2021
The Chargers make their prime time debut at SoFi Stadium, hosting the Raiders on ESPN's Monday Night Football for the first time since a 22-14 victory in 2012. The 2021 season will mark the third-straight year for Los Angeles with a prime-time matchup against the Raiders. Last year on Thursday Night Football, Los Angeles mounted a second-half comeback victory at Las Vegas that Justin Herbert capped with a game-winning rushing touchdown in overtime.