The Chargers kickoff their 2025 regular season with an AFC West showdown.
The Bolts will take on the Chiefs in São Paulo, Brazil in Week 1. Kickoff is on Friday at 5:00 p.m. (PT).
Ahead of the season opener, NFL media from across the internet have made their predictions on who they believe will win the game between the Chargers and the Chiefs on Friday night.
| Media Member | Publication | Pick |
|---|---|---|
| Ali Bhanpuri | NFL.com | Chiefs |
| Tom Blair | NFL.com | Chiefs |
| Brooke Cersosimo | NFL.com | Chiefs |
| Gennaro Filice | NFL.com | Chiefs |
| Dan Parr | NFL.com | Chiefs |
| Mike Florio | Pro Football Talk | Chiefs |
| Chris Simms | Pro Football Talk | Chiefs |
| Albert Breer | The MMQB | Chiefs |
| Conor Orr | The MMQB | Chargers |
| Gilberto Manzano | The MMQB | Chiefs |
| Matt Verderame | The MMQB | Chiefs |
| John Pluym | The MMQB | Chiefs |
| Mitch Goldich | The MMQB | Chiefs |
| Claire Brennan | The MMQB | Chiefs |
| Matt Bowen | ESPN | Chiefs |
| Mike Clay | ESPN | Chiefs |
| Jeremy Fowler | ESPN | Chiefs |
| Dan Graziano | ESPN | Chiefs |
| Kalyn Kahler | ESPN | Chiefs |
| Pamela Maldonado | ESPN | Chiefs |
| Eric Moody | ESPN | Chiefs |
| Jason Reid | ESPN | Chiefs |
| Lindsey Thiry | ESPN | Chiefs |
| Seth Wickersham | ESPN | Chargers |
| Pete Prisco | CBS Sports | Chiefs |
| Cody Benjamin | CBS Sports | Chiefs |
| Jared Dubin | CBS Sports | Chiefs |
| Ryan Wilson | CBS Sports | Chiefs |
| John Breech | CBS Sports | Chiefs |
| Tyler Sullivan | CBS Sports | Chiefs |
| Dave Richard | CBS Sports | Chargers |
| Jamey Eisenberg | CBS Sports | Chiefs |
