After hitting a home run with the 17th pick by selecting FSU safety Derwin James, the Bolts are back at it again tonight.
A number of prospects with first-round grades often slip through the cracks, allowing teams to add another high-impact player.
That's exactly what happened the past two years when the Chargers nabbed Hunter Henry and Forrest Lamp after both were assumed to be first-round locks heading into the draft.
L.A. hopes for similar luck tonight when it's their turn on the clock with the 48th overall selection.
So, who are some of the top players still available?
Here is a look at who draft experts have at the top of their boards heading into tonight:
ESPN's Mel Kiper, Jr.
Josh Jackson, CB, Iowa
Derrius Guice, RB, LSU
Justin Reid, S, Stanford
Dallas Goedert, TE, South Dakota State
Will Hernandez, G, UTEP
Harold Landry, OLB, Boston College
Ronald Jones, RB, USC
Donte Jackson, CB, LSU
Geron Christian, OT, Louisville
James Daniels, C, Iowa
Mike Gesicki, TE, Penn State
Uchenna Nwosu, OLB, USC
Isaiah Oliver, CB, Colorado
Mason Rudolph, QB, Oklahoma State
Nick Chubb, RB, Georgia
Anthony Miller, WR, Memphis
D.J. Chark, WR, LSU
Ronnie Harrison, S, Alabama
Courtland Sutton, WR, SMU
Connor Williams, OT, Texas
Maurice Hurst, DT, Michigan
Lorenzo Carter, OLB, Georgia
Jessie Bates, S, Wake Forest
Christian Kirk, WR, Texas A&M
Ian Thomas, TE, Indiana
NFL Network's Lance Zierlein
Nick Chubb, RB, Georgia
Will Hernandez, G, UTEP
Austin Corbett, OL, Nevada
Josh Jackson, CB, Iowa
Harold Landry, DE, Boston College
Connor Williams, OL, Texas
Isaiah Oliver, CB, Colorado
D.J. Chark, WR, LSU
Carlton Davis, CB, Auburn
Mason Rudolph, QB, Oklahoma State
Donte Jackson, CB, LSU
James Daniels, C, Iowa
Justin Reid, S, Stanford
Lorenzo Carter, LB, Georgia
Courtland Sutton, WR, SMU
Joseph Noteboom, OT, TCU
Darius Leonard, LB, South Carolina State
Dallas Goedert, TE, South Dakota State
CBS Sports' Chris Trapasso
Courtland Sutton, WR, SMU
Maurice Hurst, DT, Michigan
Will Hernandez, G, UTEP
Josh Jackson, CB, Iowa
Mason Rudolph, QB, Oklahoma State
Derrius Guice, RB, LSU
Ogbonnia Okoronkwo, OLB, Oklahoma
James Washington, WR, Oklahoma State
Orlando Brown, OT, Oklahoma
Isaiah Oliver, CB, Colorado
Connor Williams, OT/G, Texas
Dorian O'Daniel, LB, Clemson
Michael Gallup, WR, Colorado State
Ronald Jones, RB, USC
Chukwuma Okorafor, OT, Western Michigan
