It's a chance for a final impression.
The Chargers will play their preseason finale Saturday night on the road against the 49ers. Kickoff is at 5:30 p.m. (PT).
Here are five players to watch in the Chargers fourth and final preseason game:
1. CB Nikko Reed
Reed flashed early on in training camp before he missed practice time while working through something physically.
But the rookie undrafted free agent ended the summer on a high note with an interception in the final camp practice on Thursday.
Has the cornerback done enough to make the 53-man roster? That's still up in the air.
Reed surely has a chance to sway the front office and coaching staff with another eye-popping game against the 49ers.
2. OL Branson Taylor
The Chargers starting offensive line is set, and the next two reserve players are also cemented in Jamaree Salyer and Andre James.
We're putting Taylor on this list because he'll get a chance to show what he can do at tackle on Saturday night.
Taylor, the Chargers 2025 sixth-round pick, played tackle at Pittsburgh but transitioned to guard upon arriving to the Bolts. But he recently moved back to tackle in practice in an effort to help figure out another potential option at swing tackle.
If Taylor plays well in the finale, he could thrust himself into a key reserve role once the regular season arrives.
3. S RJ Mickens
The Chargers defense will be paced by a trio of veteran safeties in 2025, a group that affects how the rest of the unit plays in front of them.
But the fourth (or maybe fifth?) safety on the Chargers roster will have to contribute on special teams while staying ready to help on defense.
Where does Mickens land in that group?
The recent sixth-round draft pick has flashed in both practices and games, even if he needs a little fine tuning in finishing plays for takeaways.
It will be interesting to see what the Chargers do in the secondary with Tony Jefferson and Mickens when the 53-man roster deadline arrives.
4. RB Raheim Sanders
With Najee Harris still on the Non-Football Injury List, Omarion Hampton has stepped into the role of RB1 for the Chargers.
Hassan Haskins then drew praise from Chargers Head Coach Jim Harbaugh on Thursday for both his rushing ability and special teams skills.
But what about the third running back on the roster?
Jaret Patterson missed the past two weeks of practice while Kimani Vidal didn't practice for the final three days of camp.
That leaves Sanders and Nyheim Miller-Hines as the only healthy running backs on the roster.
Simply put: if Patterson and Vidal continue to work through something physically, Sanders could find himself on the 53-man roster with an impressive showing in Santa Clara.
View photos of the Chargers roster as of Aug. 18, 2025.
#0 | LB | Daiyan Henley
#0 | LB | Daiyan Henley
#1 | WR | Quentin Johnston
#1 | WR | Quentin Johnston
#2 | DB | Elijah Molden
#2 | DB | Elijah Molden
#3 | S | Derwin James, Jr.
#3 | S | Derwin James, Jr.
#4 | QB | Taylor Heinicke
#4 | QB | Taylor Heinicke
#5 | QB | Trey Lance
#5 | QB | Trey Lance
#6 | LB | Denzel Perryman
#6 | LB | Denzel Perryman
#7 | RB | DJ Uiagalelei
#7 | RB | DJ Uiagalelei
#8 | QB | Omarion Hampton
#8 | QB | Omarion Hampton
#9 | WR | Tre' Harris
#9 | WR | Tre' Harris
#10 | QB | Justin Herbert
#10 | QB | Justin Herbert
#11 | K | Cameron Dicker
#11 | K | Cameron Dicker
#12 | WR | Derius Daivs
#12 | WR | Derius Daivs
#13 | WR | Keenan Allen
#13 | WR | Keenan Allen
#15 | WR | Ladd McConkey
#15 | WR | Ladd McConkey
#16 | P | JK Scott
#16 | P | JK Scott
#20 | CB | Cam Hart
#20 | CB | Cam Hart
#22 | RB | Najee Harris (*Active/Non-Football Injury)*
#22 | RB | Najee Harris (*Active/Non-Football Injury)*
#23 | S | Tony Jefferson
#23 | S | Tony Jefferson
#24 | CB | Benjamin St-Juste
#24 | CB | Benjamin St-Juste
#25 | LB | Junior Colson
#25 | LB | Junior Colson
#26 | CB | Donte Jackson
#26 | CB | Donte Jackson
#27 | S | RJ Mickens
#27 | S | RJ Mickens
#27 | WR | JaQuae Jackson
#27 | WR | JaQuae Jackson
#28 | RB | Hassan Haskins
#28 | RB | Hassan Haskins
#29 | CB | Tarheeb Still
#29 | CB | Tarheeb Still
#30 | RB | Kimani Vidal
#30 | RB | Kimani Vidal
#31 | DB | Trikweze Bridges
#31 | DB | Trikweze Bridges
#31 | RB | Nyheim Miller-Hines
#31 | RB | Nyheim Miller-Hines
#32 | S | Alohi Gilman
#32 | S | Alohi Gilman
#33 | DB | Deane Leonard
#33 | DB | Deane Leonard
#34 | RB | Jaret Patterson
#34 | RB | Jaret Patterson
#35 | S | Jaylen Jones
#35 | S | Jaylen Jones
#35 | RB | Raheim Sanders
#35 | RB | Raheim Sanders
#36 | DB | Ja'Sir Taylor
#36 | DB | Ja'Sir Taylor
#37 | CB | Harrison Hand
#37 | CB | Harrison Hand
#37 | CB | Jordan Oladokun (*Reserve/Injured)*
#37 | CB | Jordan Oladokun (*Reserve/Injured)*
#37 | WR | Luke Grimm
#37 | WR | Luke Grimm
#38 | LB | Emany Johnson
#38 | LB | Emany Johnson
#38 | WR | Dalevon Campbell
#38 | WR | Dalevon Campbell
#39 | CB | Eric Rogers
#39 | CB | Eric Rogers
#39 | WR | Jaylen Johnson
#39 | WR | Jaylen Johnson
#40 | S | Kendall Williamson
#40 | S | Kendall Williamson
#41 | TE | Stevo Klotz
#41 | TE | Stevo Klotz
#41 | CB | Nehemiah Shelton
#41 | CB | Nehemiah Shelton
#42 | TE | Tucker Fisk
#42 | TE | Tucker Fisk
#43 | LB | Troy Dye
#43 | LB | Troy Dye
#44 | FB/DL | Scott Matlock
#44 | FB/DL | Scott Matlock
#45 | OLB | Tuli Tuipulotu
#45 | OLB | Tuli Tuipulotu
#46 | CB | Nikko Reed
#46 | CB | Nikko Reed
#47 | LS | Josh Harris
#47 | LS | Josh Harris
#48 | OLB | Bud Dupree
#48 | OLB | Bud Dupree
#49 | CB | Myles Purchase
#49 | CB | Myles Purchase
#49 | TE | Thomas Yassmin
#49 | TE | Thomas Yassmin
#50 | OLB | Caleb Murphy
#50 | OLB | Caleb Murphy
#52 | OLB | Khalil Mack
#52 | OLB | Khalil Mack
#53 | LB | Del'Shawn Phillips (*Active/Physically Unable to Perform)*
#53 | LB | Del'Shawn Phillips (*Active/Physically Unable to Perform)*
#54 | OLB | Kyle Kennard
#54 | OLB | Kyle Kennard
#56 | LB | Kana'i Mauga
#56 | LB | Kana'i Mauga
#57 | OLB | Tre'Mon Morris-Brash
#57 | OLB | Tre'Mon Morris-Brash
#58 | LB | Marlowe Wax
#58 | LB | Marlowe Wax
#59 | OLB | Kylan Guidry
#59 | OLB | Kylan Guidry
#60 | DL | Nesta Jade Silvera
#60 | DL | Nesta Jade Silvera
#61 | G | Karsen Barnhart
#61 | G | Karsen Barnhart
#62 | G | Nash Jones
#62 | G | Nash Jones
#63 | C | Josh Kaltenberger
#63 | C | Josh Kaltenberger
#65 | T | Corey Stewart
#65 | T | Corey Stewart
#67 | T | Savion Washington (*Reserve/Physically Unable to Perform)*
#67 | T | Savion Washington (*Reserve/Physically Unable to Perform)*
#68 | OL | Jamaree Salyer
#68 | OL | Jamaree Salyer
#69 | DL | Josh Fuga (*Reserve/Injured)*
#69 | DL | Josh Fuga (*Reserve/Injured)*
#70 | T | Rashawn Slater (*Reserve/Injured)*
#70 | T | Rashawn Slater (*Reserve/Injured)*
#71 | G | Branson Taylor
#71 | G | Branson Taylor
#72 | OT | David Sharpe
#72 | OT | David Sharpe
#73 | G | Mekhi Becton
#73 | G | Mekhi Becton
#74 | OT | Ryan Nelson
#74 | OT | Ryan Nelson
#75 | C | Bradley Bozeman
#75 | C | Bradley Bozeman
#76 | T | Joe Alt
#76 | T | Joe Alt
#77 | G | Zion Johnson
#77 | G | Zion Johnson
#78 | C | Andre James
#78 | C | Andre James
#79 | G/T | Trey Pipkins III
#79 | G/T | Trey Pipkins III
#82 | WR | Brenden Rice
#82 | WR | Brenden Rice
#83 | TE | Tyler Conklin
#83 | TE | Tyler Conklin
#84 | WR | KeAndre Lambert-Smith
#84 | WR | KeAndre Lambert-Smith
#86 | TE | Oronde Gadsden
#86 | TE | Oronde Gadsden
#87 | WR | Dez Fitzpatrick (*Reserve/Injured)*
#87 | WR | Dez Fitzpatrick (*Reserve/Injured)*
#88 | WR | Jalen Reagor
#88 | WR | Jalen Reagor
#89 | TE | Will Dissly
#89 | TE | Will Dissly
#90 | DL | Tear Tart
#90 | DL | Tear Tart
#91 | DL | Da'Shawn Hand
#91 | DL | Da'Shawn Hand
#92 | DL | Justin Eboigbe
#92 | DL | Justin Eboigbe
#93 | DL | Otito Ogbonnia
#93 | DL | Otito Ogbonnia
#94 | DL | TeRah Edwards
#94 | DL | TeRah Edwards
#96 | DL | Naquan Jones
#96 | DL | Naquan Jones
#97 | OLB | Garmon Randolph
#97 | OLB | Garmon Randolph
#98 | DL | Christopher Hinton
#98 | DL | Christopher Hinton
#99 | DT | Jamaree Caldwell
#99 | DT | Jamaree Caldwell
5. QB Trey Lance
Lance will start Saturday but we won't see much of him as Harbaugh noted he'll only play a series or two.
But it will be a chance for Lance to put an exclamation point on what has been a superb summer for him.
The former No. 3 overall pick has hit big pass plays and moved the chains with his legs, all while not turning the ball over and displaying a calming presence in the pocket.
Will the Chargers keep two or three quarterbacks next week? We'll see what the front office decides to do.
Either way, there's no doubt Lance has turned heads since joining the Chargers.
