Justin Herbert did not practice Friday and instead worked off to the side for rehab work at UNC Charlotte.
The Chargers quarterback is listed as questionable for Sunday's road matchup in Pittsburgh.
Herbert, who said he is dealing with a high ankle sprain, added Friday that his status is "something that's yet to be decided" ahead of Week 3.
"Every day it's been getting better," Herbert said. "It's just getting it to a point where you feel comfortable going out there and being able to move.
"It's a fast game out there, and just being able to protect yourself and get around and handle all those things," Herbert added.
Chargers Head Coach Jim Harbaugh added: "Justin's doing everything necessary to be able to play on Sunday."
Herbert dealt with an injury to his right plantar fascia in training camp but said Friday that injury is in the past and that his ankle sprain doesn't affect it.
Herbert said his biggest focus is on managing the pain in his ankle while making sure he is mobile enough in the pocket.
"It's not great," Herbert said. "It is what it is and it's all about getting treatment and getting in there and making sure that it's at its best and doing everything I can to limit the swelling, limit the pain and just keep things moving forward."
He later added: "It's been tight, but doing everything you can to limit the swelling and making sure you feel stable, especially having the whole ankle stable whenever you're putting to a cleat or shoe and going out there. Especially playing quarterback, being able to move your feet, move around, step up. do all the things that a quarterback needs to do."
Herbert noted that current treatment includes "icing, compression, just making sure I'm off my feet, doing everything I can to limit the swelling, to ease the pain."
He added: "Whatever it takes to get to moving, running, testing it out and making sure that I'm good to go."
Herbert did not practice Wednesday but was limited Thursday. He then did not practice on Friday.
When asked how much work he's gotten in practice this week, Herbert said: "Not a ton. Have kind of thrown the ball a little bit. Did some rehab today, did everything that I could, but it's just seeing how it feels and continuing to progress from there."
Harbaugh said Herbert's practice status Friday "was just what was prescribed by the medical experts, trainers, doctors."
If Herbert cannot play, either Easton Stick or Taylor Heinicke would be in line to start, but Harbaugh did not reveal a possible starter.
Herbert said that he hopes it is his decision on whether or not he plays but praised the Chargers medical staff for their work and dedication this week.
"Thankfully we've got a great training staff, coaching staff that all work together in such a great way and they communicate," Herbert said. "I think they've always been so understanding and helpful.
"I would never step foot on a field that I didn't feel comfortable playing in," added Herbert, who has dealt with a myriad of injury the past two seasons. "Whether it's been the ribs or whether it's been broken fingers, I've felt comfortable and felt ready and prepared to go out there. So I know that we'll do the same process and we'll see what it plays out."
