Los Angeles Chargers at San Francisco 49ers, August 25, 2023

History: Los Angeles Chargers vs. San Francisco 49ers

The first matchup between these two teams was on September 17, 1972, the 49ers took a 34-3 win over the Chargers. The last regular season matchup was on November 13, 2022, where the 49ers took a 22-16 win over the Chargers.

Players and Coaches to Know

Los Angeles Chargers

- Head Coach Brandon Staley

- Quarterback Justin Herbert

- Wide Receiver Keenan Allen

- Tackle Rashawn Slater

- Outside Linebacker Khalil Mack

San Francisco 49ers

- Head Coach Kyle Shanahan

- Quarterback Brock Purdy

- Running Back Christian McCafferey

- Tight End George Kittle

- Linebacker Fred Warner